Overview: Dengue virus (DENV) is an enveloped, positive-sense RNA virus (Flavivirus) causing dengue fever and severe dengue (dengue hemorrhagic fever / shock syndrome).

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Transmission: : Vector borne – DENV is transmitted mainly through the bite of infected female Aedes mosquitoes, especially Aedes aegypti and Aedes albopictus.

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Disease: Acute febrile illness that can progress to vascular leakage, thrombocytopenia, hemorrhage, and shock in severe cases. Inside infected cells, dengue virus induces complex membrane vesicle structures where viral replication occurs. Approximately 14 million cases are recorded worldwide each year, with 11 000 death.

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Risk group: DENV is classified as Risk Group 3 (RG3). Propagation of infectious virus requires BSL-3 containment

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Imaging sites within Germany:

Heidelberg University Medical Faculty - CIID/ IDIP​

Helmholtz Munich - Institute of Virology​​

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​Additional resources: 

(Work in progress)